Understanding the Allergic or Atopic March

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The journey of allergic diseases in individuals, often beginning in infancy, is known as the allergic march or atopic march. This progression typically follows a specific pattern, affecting the quality of life and potentially leading to serious health concerns.

What is Atopy?

Atopy refers to the genetic tendency to develop allergic diseases, which include food allergies, allergic rhinitis, asthma, and atopic dermatitis (eczema). These conditions often manifest early in life and progress over time.

The Natural History of Allergic Diseases

  1. Dry Skin at Birth:
    • Many infants developed dry skin early in life, which can be the first sign of potential allergic conditions.
  2. Eczema (Atopic Dermatitis):
    • It appears in the first few weeks or months of life, compromising the skin’s barrier and increasing the risk of infection and affecting quality of life.
  3. Food Allergies:
    • It often develops in the first few months or years as the immune system overreacts to allergens entering through the gut or gastrointestinal tract.
  4. Rhinitis (Nasal Allergies):
    • Typically emerges after age three, involving inflammation of the nasal passages.
  5. Asthma:
    • It can develop within the first few months to years of life, often progressing from early wheezing related to viral infections.

The Impact of Allergic Diseases

Allergic conditions can severely affect an individual’s quality of life and can be life-threatening, making early recognition and management crucial.

Preventing the Allergic March: Is it Possible?

Early intervention can reduce the risk of developing allergic diseases. Here’s what current research suggests:

  1. Avoiding Environmental Triggers:
    • Avoiding tobacco smoke, pollution, house dust, animal dander and viruses like RSV may help prevent asthma.
  2. Breastfeeding:
    • Supports lung development and improves the immune system thus reducing respiratory infection potentially lowering the risk of asthma.
  3. Dust Mite Control:
    • Keeping the home free of dust mites can help prevent asthma and atopic dermatitis.
  4. Skin Moisturization:
    • Early studies suggested that moisturizers could prevent eczema, though recent research needs to be more consistent.

Ongoing Research

Researchers continue to explore strategies to prevent eczema, allergies, and asthma, with ongoing studies needed to develop reliable prevention guidelines.


The allergic march illustrates the progression of allergic diseases from infancy through early childhood. Understanding this march allows for early interventions that can significantly impact long-term health outcomes. Proactive measures such as environmental control, and supportive breastfeeding practices offer hope in managing and potentially preventing these conditions. Continued research is essential to develop robust prevention strategies, offering a better quality of life for those at risk of allergic diseases.

If you or a family member have symptoms of allergy, secure your appointment today. For more information or to schedule an appointment, call us at 8711-4141.

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